Abstract
The performance of periodontal diagnostic tests is often evaluated by estimating their sensitivity and specificity with respect to a traditionally accepted standard test regarded as a "gold standard" in making the diagnosis. Correlated samples of binary data arise in dental research. The fundamental unit for analysis is occasionally the site rather than the patient in site-specific dental studies. Statistical methods that take into account the within-patient correlation should be employed to estimate the sensitivity and the specificity of diagnostic tests since site-specific results within a patient can be highly correlated. Several statistical methods are introduced for the estimation of the sensitivity and the specificity of site-specific diagnostic tests; these techniques are applied to the data from a study involving an enzymatic diagnostic test to motivate and illustrate the estimation of the sensitivity and the specificity of periodontal diagnostic tests.
Original language | English (US) |
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Pages (from-to) | 351-354 |
Number of pages | 4 |
Journal | Journal of Periodontal Research |
Volume | 32 |
Issue number | 4 |
DOIs | |
State | Published - May 1997 |
Keywords
- Correlated data
- Sensitivity
- Specificity
ASJC Scopus subject areas
- Periodontics