Stem Cells: A Renaissance in Human Biology Research

Jun Wu, Juan Carlos Izpisua Belmonte

Research output: Contribution to journalReview article

36 Citations (Scopus)

Abstract

The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.

Original languageEnglish (US)
Pages (from-to)1572-1585
Number of pages14
JournalCell
Volume165
Issue number7
DOIs
StatePublished - Jun 16 2016
Externally publishedYes

Fingerprint

Stem cells
Stem Cells
Research
Innovation
Inventions
Aptitude
Human Development
Embryonic Development
Research Personnel
Renaissance
Therapeutics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Stem Cells : A Renaissance in Human Biology Research. / Wu, Jun; Izpisua Belmonte, Juan Carlos.

In: Cell, Vol. 165, No. 7, 16.06.2016, p. 1572-1585.

Research output: Contribution to journalReview article

Wu, J & Izpisua Belmonte, JC 2016, 'Stem Cells: A Renaissance in Human Biology Research', Cell, vol. 165, no. 7, pp. 1572-1585. https://doi.org/10.1016/j.cell.2016.05.043
Wu, Jun ; Izpisua Belmonte, Juan Carlos. / Stem Cells : A Renaissance in Human Biology Research. In: Cell. 2016 ; Vol. 165, No. 7. pp. 1572-1585.
@article{c82c0339a9f8428ba3f79650aa49517c,
title = "Stem Cells: A Renaissance in Human Biology Research",
abstract = "The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell {"}omics{"} and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.",
author = "Jun Wu and {Izpisua Belmonte}, {Juan Carlos}",
year = "2016",
month = "6",
day = "16",
doi = "10.1016/j.cell.2016.05.043",
language = "English (US)",
volume = "165",
pages = "1572--1585",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "7",

}

TY - JOUR

T1 - Stem Cells

T2 - A Renaissance in Human Biology Research

AU - Wu, Jun

AU - Izpisua Belmonte, Juan Carlos

PY - 2016/6/16

Y1 - 2016/6/16

N2 - The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.

AB - The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.

UR - http://www.scopus.com/inward/record.url?scp=84975282927&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84975282927&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2016.05.043

DO - 10.1016/j.cell.2016.05.043

M3 - Review article

C2 - 27315475

AN - SCOPUS:84975282927

VL - 165

SP - 1572

EP - 1585

JO - Cell

JF - Cell

SN - 0092-8674

IS - 7

ER -