Stem cells and interspecies chimaeras

Jun Wu, Henry T. Greely, Rudolf Jaenisch, Hiromitsu Nakauchi, Janet Rossant, Juan Carlos Izpisua Belmonte

Research output: Contribution to journalReview article

56 Scopus citations


Chimaeras are both monsters of the ancient imagination and a long-established research tool. Recent advances, particularly those dealing with the identification and generation of various kinds of stem cells, have broadened the repertoire and utility of mammalian interspecies chimaeras and carved out new paths towards understanding fundamental biology as well as potential clinical applications.

Original languageEnglish (US)
Pages (from-to)51-59
Number of pages9
Issue number7631
StatePublished - Dec 1 2016
Externally publishedYes


ASJC Scopus subject areas

  • General

Cite this

Wu, J., Greely, H. T., Jaenisch, R., Nakauchi, H., Rossant, J., & Belmonte, J. C. I. (2016). Stem cells and interspecies chimaeras. Nature, 540(7631), 51-59.