Stereospecific synthesis of trans-arachidonic acids

U. Murali Krishna, M. Muralidhar Reddy, Jianing Xia, J. R. Falck, Michael Balazy

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

An effective synthesis is described for the preparation of all four mono trans isomers of arachidonic acid via deoxidation of epoxide precursors with lithium diphenylphosphide and quaternization with methyl iodide.

Original languageEnglish (US)
Pages (from-to)2415-2418
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume11
Issue number18
DOIs
StatePublished - Sep 17 2001

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Cite this