Stereotactic body radiation therapy for oligometastases

Simon S. Lo, Achilles J. Fakiris, Bin S. Teh, Higinia R. Cardenes, Mark A. Henderson, Jeffrey A. Forquer, Lech Papiez, Ronald C. McGarry, Jian Z. Wang, Kaile Li, Nina A. Mayr, Robert D. Timmerman

Research output: Contribution to journalReview articlepeer-review

54 Scopus citations

Abstract

The standard treatment for metastatic cancer is systemic therapy. However, in a subset of patients with limited extracranial metastases or oligometastases, local ablative therapy in combination with systemic therapy may improve treatment outcomes. Stereotactic body radiation therapy (SBRT) has emerged as a novel approach for local ablation of extracranial oligometastases. There is a good body of experience in the use of SBRT for the treatment of oligometastases in various sites including the lung, the liver and the spine with promising results. This article provides an overview of the use of SBRT in the management of extracranial oligometastases.

Original languageEnglish (US)
Pages (from-to)621-635
Number of pages15
JournalExpert Review of Anticancer Therapy
Volume9
Issue number5
DOIs
StatePublished - 2009

Keywords

  • Body
  • Oligometastases
  • Radiation therapy
  • Stereotactic

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)

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