Stereotactic body radiation therapy (SBRT) for genitourinary malignancies.

Bin S. Teh, Hiromichi Ishiyama, Thomas Mathews, B. Xu, E. Brian Butler, Nina A. Mayr, Simon S. Lo, Jiade J. Lu, Angel I. Blanco, Arnold C. Paulino, Robert D. Timmerman

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

Stereotactic body radiation therapy (SBRT) is a novel treatment modality in radiation oncology that delivers a very high dose of radiation to the tumor target with high precision using single or a small number of fractions. SBRT is the result of technological advances in patient/tumor immobilization, image guidance, and treatment planning and delivery. This modality is safe and effective in both early stage primary cancer and oligometastases. Compared to the use of stereotactic radiosurgery for other tumor sites, SBRT is slow to be adopted in the management of genitourinary malignancies. There are now emerging data that show the safety and efficacy of this treatment modality in genitourinary (GU) malignancies especially in prostate cancer and renal cell carcinoma. Preclinical data, clinical experience, and challenges are reviewed and discussed.

Original languageEnglish (US)
Pages (from-to)255-262
Number of pages8
JournalDiscovery Medicine
Volume10
Issue number52
StatePublished - Sep 2010

ASJC Scopus subject areas

  • Medicine(all)

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    Teh, B. S., Ishiyama, H., Mathews, T., Xu, B., Butler, E. B., Mayr, N. A., Lo, S. S., Lu, J. J., Blanco, A. I., Paulino, A. C., & Timmerman, R. D. (2010). Stereotactic body radiation therapy (SBRT) for genitourinary malignancies. Discovery Medicine, 10(52), 255-262.