TY - JOUR
T1 - Stereotactic radiotherapy of primary lung cancer and other targets
T2 - Results of consultant meeting of the international atomic energy agency
AU - Nagata, Yasushi
AU - Wulf, Joern
AU - Lax, Ingmar
AU - Timmerman, Robert
AU - Zimmermann, Frank
AU - Stojkovski, Igor
AU - Jeremic, Branislav
PY - 2011/3/1
Y1 - 2011/3/1
N2 - To evaluate the current status of stereotactic body radiotherapy (SBRT) and identify both advantages and disadvantages of its use in developing countries, a meeting composed of consultants of the International Atomic Energy Agency was held in Vienna in November 2006. Owing to continuous developments in the field, the meeting was extended by subsequent discussions and correspondence (2007-2010), which led to the summary presented here. The advantages and disadvantages of SBRT expected to be encountered in developing countries were identified. The definitions, typical treatment courses, and clinical results were presented. Thereafter, minimal methodology/technology requirements for SBRT were evaluated. Finally, characteristics of SBRT for developing countries were recommended. Patients for SBRT should be carefully selected, because single high-dose radiotherapy may cause serious complications in some serial organs at risk. Clinical experiences have been reported in some populations of lung cancer, lung oligometastases, liver cancer, pancreas cancer, and kidney cancer. Despite the disadvantages expected to be experienced in developing countries, SBRT using fewer fractions may be useful in selected patients with various extracranial cancers with favorable outcome and low toxicity.
AB - To evaluate the current status of stereotactic body radiotherapy (SBRT) and identify both advantages and disadvantages of its use in developing countries, a meeting composed of consultants of the International Atomic Energy Agency was held in Vienna in November 2006. Owing to continuous developments in the field, the meeting was extended by subsequent discussions and correspondence (2007-2010), which led to the summary presented here. The advantages and disadvantages of SBRT expected to be encountered in developing countries were identified. The definitions, typical treatment courses, and clinical results were presented. Thereafter, minimal methodology/technology requirements for SBRT were evaluated. Finally, characteristics of SBRT for developing countries were recommended. Patients for SBRT should be carefully selected, because single high-dose radiotherapy may cause serious complications in some serial organs at risk. Clinical experiences have been reported in some populations of lung cancer, lung oligometastases, liver cancer, pancreas cancer, and kidney cancer. Despite the disadvantages expected to be experienced in developing countries, SBRT using fewer fractions may be useful in selected patients with various extracranial cancers with favorable outcome and low toxicity.
KW - Kidney cancer
KW - Liver cancer
KW - Lung metastases
KW - Non-small-cell lung cancer
KW - Pancreatic cancer
KW - Stereotactic body radiation therapy
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U2 - 10.1016/j.ijrobp.2010.10.004
DO - 10.1016/j.ijrobp.2010.10.004
M3 - Review article
C2 - 21281896
AN - SCOPUS:79551469538
SN - 0360-3016
VL - 79
SP - 660
EP - 669
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
IS - 3
ER -