Stevens-Johnson syndrome in children

Research output: Contribution to journalArticle

80 Scopus citations

Abstract

During a 22-year period 51 cases of Stevens-Johnson syndrome (SJS) occurred in infants and children who ranged in age from 3 months to 14 years. Fifty-six percent of patients had an ante-cedent upper respiratory tract infection or non-specific viral infection, and 67% had received a prescription medication in the 3 weeks before onset of SJS. Nineteen patients (37%) were treated with adrenocorticosteroid medication during their hospitalization. Age, sex, duration of illness, body temperature on admission and history of antecedent medication were similar for the steroid-and non-steroid-treated patients. Rates of infection and overall complications were significantly greater in steroid-treated patients than in those treated symptomatically. These observations suggest that steroid drugs should not be used for treatment of SJS in infants and children.

Original languageEnglish (US)
Pages (from-to)155-158
Number of pages4
JournalPediatric infectious disease
Volume1
Issue number3
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)

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