Streptozotocin in advanced small cell bronchogenic carcinoma: An ineffective nonmyelosuppressive agent

P. A. Bunn, D. C. Ihde, M. H. Cohen, S. E. Shackney, J. D. Minna

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Thirteen patients with advanced small cell bronchogenic carcinoma (SCBC) received at least three weekly cycles of iv streptozotocin (STZ). There were no objective responses. Four patients progressed by the third week of therapy and an additional eight by the fourth week. Toxicity was acceptable especially in view of the extensive prior therapy. STZ is unlikely to be of benefit in combination chemotherapy regimens for SCBC.

Original languageEnglish (US)
Pages (from-to)479-481
Number of pages3
JournalCancer Treatment Reports
Volume62
Issue number3
StatePublished - Dec 1 1978

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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