Structural and genetic studies on chicken 7S immunoglobulin allotypes. III. Proposed nomenclature for the CS-1 gene alleles

E. K. Wakeland, J. M. Foppoli, A. A. Benedict

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A survey of 47 inbred or partially inbred chicken lines derived from 5 sources in the United States and Europe revealed considerable genetic polymorphism in the structural gene (CS-1) responsible for the production of the predominant chicken 7S Ig heavy chain. A minimum of 10 alleles of the CS-1 gene were detected as unique combinations or phenogroups of CS-1 specificities. A system of nomenclature for CS-1 alleles was developed and 6 homozygous lines were designated as prototype lines. The remaining four CS-1 alleles occurred only in lines that were polymorphic for 7S Ig allotypic specificities.

Original languageEnglish (US)
Pages (from-to)1218-1222
Number of pages5
JournalJournal of Immunology
Volume119
Issue number4
StatePublished - Dec 1 1977

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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