Abstract
Summary: Along with their mutating sequences, protein structures change in time. Analyzing a formate dehydrogenase domain that is evolutionarily related to ferredoxin, but simultaneously contains all the structural elements of a β-Grasp fold, we illustrate here a mechanism termed as structural drift, by which changes to a protein fold can occur.
Original language | English (US) |
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Pages (from-to) | 1308-1310 |
Number of pages | 3 |
Journal | Bioinformatics |
Volume | 21 |
Issue number | 8 |
DOIs | |
State | Published - Apr 15 2005 |
ASJC Scopus subject areas
- Statistics and Probability
- Biochemistry
- Molecular Biology
- Computer Science Applications
- Computational Theory and Mathematics
- Computational Mathematics