Structural studies on protein products of murine chromosome 17. III. Partial amino acid sequence of an H-2K(q) molecule

R. G. Cook, E. S. Vitetta, J. W. Uhr, J. Klein, C. E. Wilde IIIrd, J. D. Capra

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Abstract

Twenty-one of the amino terminal twenty-seven amino acid residues have been assigned in the murine H-2K(q) molecule and several additional assignments and corrections have been made in both the H-2K(k) and H-2K(b) molecules. The study shows that H-2K(k) and H-K(q), which are serologically related, have an identical amino acid sequence for all twenty positions that can be compared, the H-2K(k) and H-2K(q) molecules differ from H-2K(b) at only two positions - 9 and 22, and the additional sequence data on the H-2K(k), -K(b), and -K(q) molecules increases the already striking homology between murine and human transplantation antigens.

Original languageEnglish (US)
Pages (from-to)1015-1019
Number of pages5
JournalJournal of Immunology
Volume121
Issue number3
StatePublished - 1978

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Chromosomes, Human, Pair 17
Amino Acid Sequence
Histocompatibility Antigens
Proteins
Amino Acids
H-2K(K) antigen

ASJC Scopus subject areas

  • Immunology

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Structural studies on protein products of murine chromosome 17. III. Partial amino acid sequence of an H-2K(q) molecule. / Cook, R. G.; Vitetta, E. S.; Uhr, J. W.; Klein, J.; Wilde IIIrd, C. E.; Capra, J. D.

In: Journal of Immunology, Vol. 121, No. 3, 1978, p. 1015-1019.

Research output: Contribution to journalArticle

Cook, R. G. ; Vitetta, E. S. ; Uhr, J. W. ; Klein, J. ; Wilde IIIrd, C. E. ; Capra, J. D. / Structural studies on protein products of murine chromosome 17. III. Partial amino acid sequence of an H-2K(q) molecule. In: Journal of Immunology. 1978 ; Vol. 121, No. 3. pp. 1015-1019.
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AU - Wilde IIIrd, C. E.

AU - Capra, J. D.

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