Structure of a family of rat amylase genes

Raymond J. MacDonald, Michael M. Crerar, William F. Swain, Raymond L. Pictet, Gilles Thomas, William J. Rutter

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

The sequences of two cloned rat pancreatic amylase cDNAs comprising 95% of the mRNA sequence are reported. Analysis of cloned rat genomic DNA fragments using cloned cDNA probes indicates that the rat genome contains multiple closely related amylase genes in which the cDNA sequences are distributed within a region 9 kilobases in length and are interrupted by at least seven intervening sequences.

Original languageEnglish (US)
Pages (from-to)117-122
Number of pages6
JournalNature
Volume287
Issue number5778
DOIs
StatePublished - 1980

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Amylases
Complementary DNA
Genes
Introns
Genome
Messenger RNA
DNA

ASJC Scopus subject areas

  • General

Cite this

MacDonald, R. J., Crerar, M. M., Swain, W. F., Pictet, R. L., Thomas, G., & Rutter, W. J. (1980). Structure of a family of rat amylase genes. Nature, 287(5778), 117-122. https://doi.org/10.1038/287117a0

Structure of a family of rat amylase genes. / MacDonald, Raymond J.; Crerar, Michael M.; Swain, William F.; Pictet, Raymond L.; Thomas, Gilles; Rutter, William J.

In: Nature, Vol. 287, No. 5778, 1980, p. 117-122.

Research output: Contribution to journalArticle

MacDonald, RJ, Crerar, MM, Swain, WF, Pictet, RL, Thomas, G & Rutter, WJ 1980, 'Structure of a family of rat amylase genes', Nature, vol. 287, no. 5778, pp. 117-122. https://doi.org/10.1038/287117a0
MacDonald RJ, Crerar MM, Swain WF, Pictet RL, Thomas G, Rutter WJ. Structure of a family of rat amylase genes. Nature. 1980;287(5778):117-122. https://doi.org/10.1038/287117a0
MacDonald, Raymond J. ; Crerar, Michael M. ; Swain, William F. ; Pictet, Raymond L. ; Thomas, Gilles ; Rutter, William J. / Structure of a family of rat amylase genes. In: Nature. 1980 ; Vol. 287, No. 5778. pp. 117-122.
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