Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides

John B. MacMillan, Eugene K. Trousdale, Tadeusz F. Molinski

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

(equation presented) Neodysidenin was isolated from the marine sponge Dysidea herbacea (Keller 1889) collected on the Great Barrier Reef. The complete configuration was obtained from a combination of methods, including capillary electrophoresis of Marfey's derivatives. Neodysidenin belongs to the L-series of trichloroleucine peptides, and the configuration of the N-methyl thiazolyl alanine residue (13R) is opposite to that of dysidenin.

Original languageEnglish (US)
Pages (from-to)2721-2723
Number of pages3
JournalOrganic Letters
Volume2
Issue number17
StatePublished - Aug 24 2000

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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