Studies on Bile Acids in Rat Systemic Blood. Bile Acids and Steroids 107

Scott M Grundy, J. SJOVALL

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Rats were given tritium labelled cholic acid intraperitoneally or orally and killed by exsanguination after 24 or 48 hours. The concentration of “total cholic acid” in whole blood was calculated from the distribution of isotope in intestine and blood and previous figures for intestinal “cholic acid.” A value of about 0.08 mg/100 ml was found. Chromatographic analysis showed that more unconjugated cholic acid was present in the systemic blood than in the small intestine.

Original languageEnglish (US)
Pages (from-to)306-309
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume107
Issue number2
DOIs
StatePublished - Jun 1961

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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