Studies on Hormonal Regulation of Squalene Synthesis in Preputial Gland and Skin of the Rat

T. L. BURGESS, J. D. WILSON

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Utilizing gas-liquid chromatographic techniques, the influence of administration of testosterone, progesterone, and estradiol on the content of skin and preputial gland squalene has been studied in the castrated rat. Testosterone and, to a lesser extent, progesterone markedly enhance the squalene content of the preputial gland. Testosterone also enhances the synthesis of fatty acids from acetate-2-C14 in this tissue, suggesting that it may act in a general way to enhance fat synthesis.

Original languageEnglish (US)
Pages (from-to)747-750
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume113
Issue number3
DOIs
StatePublished - Jul 1963

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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