TY - JOUR
T1 - Studies on Hormonal Regulation of Squalene Synthesis in Preputial Gland and Skin of the Rat
AU - BURGESS, T. L.
AU - WILSON, J. D.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1963/7
Y1 - 1963/7
N2 - Utilizing gas-liquid chromatographic techniques, the influence of administration of testosterone, progesterone, and estradiol on the content of skin and preputial gland squalene has been studied in the castrated rat. Testosterone and, to a lesser extent, progesterone markedly enhance the squalene content of the preputial gland. Testosterone also enhances the synthesis of fatty acids from acetate-2-C14 in this tissue, suggesting that it may act in a general way to enhance fat synthesis.
AB - Utilizing gas-liquid chromatographic techniques, the influence of administration of testosterone, progesterone, and estradiol on the content of skin and preputial gland squalene has been studied in the castrated rat. Testosterone and, to a lesser extent, progesterone markedly enhance the squalene content of the preputial gland. Testosterone also enhances the synthesis of fatty acids from acetate-2-C14 in this tissue, suggesting that it may act in a general way to enhance fat synthesis.
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U2 - 10.3181/00379727-113-28479
DO - 10.3181/00379727-113-28479
M3 - Article
C2 - 14016990
AN - SCOPUS:0012712344
SN - 0037-9727
VL - 113
SP - 747
EP - 750
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 3
ER -