Studies toward the unique pederin family member psymberin: Structure-activity relationships, biochemical studies, and genetics identify the mode-of-action of psymberin

Medicine & Life Sciences

• psymberin 100%
• pederin 86%
• Structure-Activity Relationship 49%
• Molecular Biology 34%
• mycalamide A 10%
• Protein Biosynthesis 10%
• Ribosomal Proteins 5%
• Amides 5%
• Irritants 5%
• Caenorhabditis elegans 5%
• Biological Products 4%
• Point Mutation 4%
• Psychological Inhibition 3%
• Proteins 3%
• Aptitude 3%
• Mutation 2%
• In Vitro Techniques 2%
• Genes 1%

Chemical Compounds

• Pederin 78%
• Structure-Activity Relationship 36%
• Dihydroisocoumarins 28%
• Mycalamide A 16%
• Mutation 14%
• Protein 13%
• Irritant 12%
• Protein Synthesis 8%
• Diastereomer 7%
• Stereochemistry 7%
• Occurrence in Nature 6%
• Bioactivity 6%
• Amide 5%
• Strain 5%
• Modification 4%

Engineering & Materials Science

• Genetics 56%
• Proteins 38%
• Stereochemistry 15%
• Gene encoding 15%
• Amides 12%
• Cytotoxicity 12%
• Bioactivity 11%
• Assays 9%