Abstract
Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency due to mutations in the WAS gene expressed in hematopoietic cells. Hematopoietic stem cell transplantation (HSCT) is the treatment of choice when an appropriate human leukocyte antigen-matched donor is available. The use of the extracorporeal membrane oxygenation (ECMO) circuit to infuse donor cells for HSCT has not been previously published in the literature. We describe a case of a child who had successful engraftment after HSCT with infusion of the donor stem cells through the ECMO circuit.
Original language | English (US) |
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Pages (from-to) | 617-619 |
Number of pages | 3 |
Journal | Indian Journal of Critical Care Medicine |
Volume | 20 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2016 |
Keywords
- Engraftment
- Wiskott-Aldrich syndrome
- extracorporeal membrane oxygenation
- hematopoietic stem cell transplantation
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine