Successful engraftment after hematopoietic stem cell transplantation with infusion of donor stem cells through the extracorporeal membrane oxygenation circuit

Pilar Anton-Martin, Cindy Darnell-Bowens, Victor M. Aquino, Teresa Jones, Lakshmi Raman

Research output: Contribution to journalArticle

Abstract

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency due to mutations in the WAS gene expressed in hematopoietic cells. Hematopoietic stem cell transplantation (HSCT) is the treatment of choice when an appropriate human leukocyte antigen-matched donor is available. The use of the extracorporeal membrane oxygenation (ECMO) circuit to infuse donor cells for HSCT has not been previously published in the literature. We describe a case of a child who had successful engraftment after HSCT with infusion of the donor stem cells through the ECMO circuit.

Original languageEnglish (US)
Pages (from-to)617-619
Number of pages3
JournalIndian Journal of Critical Care Medicine
Volume20
Issue number10
DOIs
StatePublished - Oct 1 2016

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Keywords

  • Engraftment
  • extracorporeal membrane oxygenation
  • hematopoietic stem cell transplantation
  • Wiskott-Aldrich syndrome

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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