Successful large volume leukapheresis on a small infant allogeneic donor

J. Pahys, V. Fisher, M. Carneval, R. Yomtovian, R. Sarode, M. Nieder

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We successfully performed a hematopoietic stem cell apheresis on the smallest allogeneic donor reported to date, a 6.1 kg female. After placement of a dialysis catheter in the left femoral vein, the COBE Spectra was primed with one unit of paternal whole blood. Heparin and anticoagulant citrate dextrose, solution A (ACD-A) were slowly administered to the patient. Ionized calcium levels were checked hourly and calcium gluconate was given for hypocalcemia. Coagulation parameters were checked throughout the procedure. We collected 4.4 x 106 CD34+ cells/kg (recipient). The donor tolerated the procedure well and was discharged the following day. Five months later, the child manifests no obvious late effects.

Original languageEnglish (US)
Pages (from-to)339-341
Number of pages3
JournalBone Marrow Transplantation
Volume26
Issue number3
StatePublished - 2000

Fingerprint

Leukapheresis
Tissue Donors
Calcium Gluconate
Blood Component Removal
Femoral Vein
Hypocalcemia
Hematopoietic Stem Cells
Citric Acid
Anticoagulants
Heparin
Dialysis
Catheters
Calcium
Glucose

Keywords

  • Allogeneic donor
  • Infant
  • Leukapheresis

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Pahys, J., Fisher, V., Carneval, M., Yomtovian, R., Sarode, R., & Nieder, M. (2000). Successful large volume leukapheresis on a small infant allogeneic donor. Bone Marrow Transplantation, 26(3), 339-341.

Successful large volume leukapheresis on a small infant allogeneic donor. / Pahys, J.; Fisher, V.; Carneval, M.; Yomtovian, R.; Sarode, R.; Nieder, M.

In: Bone Marrow Transplantation, Vol. 26, No. 3, 2000, p. 339-341.

Research output: Contribution to journalArticle

Pahys, J, Fisher, V, Carneval, M, Yomtovian, R, Sarode, R & Nieder, M 2000, 'Successful large volume leukapheresis on a small infant allogeneic donor', Bone Marrow Transplantation, vol. 26, no. 3, pp. 339-341.
Pahys J, Fisher V, Carneval M, Yomtovian R, Sarode R, Nieder M. Successful large volume leukapheresis on a small infant allogeneic donor. Bone Marrow Transplantation. 2000;26(3):339-341.
Pahys, J. ; Fisher, V. ; Carneval, M. ; Yomtovian, R. ; Sarode, R. ; Nieder, M. / Successful large volume leukapheresis on a small infant allogeneic donor. In: Bone Marrow Transplantation. 2000 ; Vol. 26, No. 3. pp. 339-341.
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