Abstract
We successfully performed a hematopoietic stem cell apheresis on the smallest allogeneic donor reported to date, a 6.1 kg female. After placement of a dialysis catheter in the left femoral vein, the COBE Spectra was primed with one unit of paternal whole blood. Heparin and anticoagulant citrate dextrose, solution A (ACD-A) were slowly administered to the patient. Ionized calcium levels were checked hourly and calcium gluconate was given for hypocalcemia. Coagulation parameters were checked throughout the procedure. We collected 4.4 x 106 CD34+ cells/kg (recipient). The donor tolerated the procedure well and was discharged the following day. Five months later, the child manifests no obvious late effects.
Original language | English (US) |
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Pages (from-to) | 339-341 |
Number of pages | 3 |
Journal | Bone Marrow Transplantation |
Volume | 26 |
Issue number | 3 |
DOIs | |
State | Published - 2000 |
Keywords
- Allogeneic donor
- Infant
- Leukapheresis
ASJC Scopus subject areas
- Hematology
- Transplantation