Abstract
Background: Paraspinal masses are a relatively uncommon but diverse group of lesions that can be neoplastic or non-neoplastic. Peripheral primitive neuroectodermal tumors of the lumbar paraspinal region with diffuse and strong glial differentiation have never been reported before. Case Description: We report a primary paraspinal primitive neuroectodermal tumor with overwhelming glial differentiation in a 23-year-old female patient who presented with intractable right lower extremity pain. The patient underwent a 2-staged operation with gross total resection of the mass followed by intensity-modulated radiation therapy and oral temozolomide, a regimen employed for high-grade intracranial gliomas. Serial imaging revealed no evidence of recurrence after 3 years. Conclusions: Although these lesions appear to be exceptionally rare, an approach similar to that of intracranial high-grade glial tumors was effective in our experience. Our patient had no evidence of recurrence at 3-year follow-up.
Original language | English (US) |
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Pages (from-to) | 340-344 |
Number of pages | 5 |
Journal | World Neurosurgery |
Volume | 119 |
DOIs | |
State | Published - Nov 1 2018 |
Keywords
- Chemotherapy
- High glial differentiation
- Paraspinal mass
- Paraspinal neoplasm
- Paraspinal primitive neuroectodermal tumor
- Radiation
- Surgery
ASJC Scopus subject areas
- Surgery
- Clinical Neurology