Successful treatment of a skull base malignant rhabdoid tumor with surgery, chemotherapy and gamma knife-based stereotactic radiosurgery in a young child

Thomas C. Witt, Simon S. Lo, Robert D. Timmerman

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Most childhood rhabdoid tumors occur in the kidney or central nervous system but they can occur in other sites and they usually run an aggressive clinical course. We report a case of an 8-month-old boy with a right temporal bone rhabdoid tumor treated with surgery, chemotherapy and Gamma Knife-based stereotactic radiosurgery. The patient remained alive after 61 months and repeat magnetic resonance imaging (MRI) of the brain showed no evidence of recurrence. There were no obvious endocrine deficits or growth abnormalities at last follow-up. Gamma Knife-based stereotactic radiosurgery may have a role in the management of very young children with skull base tumors.

Original languageEnglish (US)
Pages (from-to)310-313
Number of pages4
JournalStereotactic and Functional Neurosurgery
Volume85
Issue number6
DOIs
StatePublished - Oct 2007

Fingerprint

Rhabdoid Tumor
Radiosurgery
Skull Base
Drug Therapy
Temporal Bone
Central Nervous System
Magnetic Resonance Imaging
Kidney
Recurrence
Brain
Therapeutics
Growth
Neoplasms

Keywords

  • Gamma Knife
  • Rhabdoid tumor
  • Young child

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

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AB - Most childhood rhabdoid tumors occur in the kidney or central nervous system but they can occur in other sites and they usually run an aggressive clinical course. We report a case of an 8-month-old boy with a right temporal bone rhabdoid tumor treated with surgery, chemotherapy and Gamma Knife-based stereotactic radiosurgery. The patient remained alive after 61 months and repeat magnetic resonance imaging (MRI) of the brain showed no evidence of recurrence. There were no obvious endocrine deficits or growth abnormalities at last follow-up. Gamma Knife-based stereotactic radiosurgery may have a role in the management of very young children with skull base tumors.

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