@article{f1bec62192a44577b579423f0bc37f03,
title = "Successful Treatment of Invasive Conidiobolus Infection during Therapy for Acute Lymphoblastic Leukemia",
abstract = "Invasive fungal infections are a serious cause of morbidity and mortality in patients with hematologic malignancies. Conidiobolus species are molds within the order Entomophthorales and may disseminate to become rapidly fatal in immunocompromised individuals. This species of fungal infections are often multidrug resistant (MDR) and present unique therapeutic challenges. Reports of Conidiobolus infections are rare in pediatric oncology. We report the successful treatment of an adolescent male with B-cell lymphoblastic leukemia and MDR invasive sinopulmonary Conidiobolus infection with emphasis on early and aggressive neutrophil support with surgical debridement. The strategies described could be applied to other MDR fungal infections. {\textcopyright}",
keywords = "Conidiobolus, granulocyte transfusions, granulocyte-macrophage colony-stimulating factor (GM-CSF), leukemia, multidrug resistance",
author = "Craig Erker and Huppler, {Anna R.} and Walsh, {Thomas J.} and McCormick, {Michael E.} and Mariko Suchi and Bhatt, {Neel S.} and Kehl, {Susan C.} and Jessica Southwood and Paul Harker-Murray",
note = "Funding Information: Received for publication May 28, 2017; accepted June 29, 2017. From the Departments of *Pediatrics; ‡Otolaryngology; §Pathology, Medical College of Wisconsin, Milwaukee, WI; and †Transplantation-Oncology Infectious Diseases Program, Weill Cornell Medical Center of Cornell University, New York City, NY. T.J.W. was supported in part for this work as a Scholar in Mucormy-cosis of the Henry Schueler Foundation. The remaining authors declare no conflict of interest. Reprints: Craig Erker, MD, Department of Pediatrics, Medical College of Wisconsin, MFRC 3018, 8701 Watertown Plank Road, Milwaukee, WI 53226 (e-mail: craigaerker@gmail.com). Copyright {\textcopyright} 2017 Wolters Kluwer Health, Inc. All rights reserved. Publisher Copyright: Copyright {\textcopyright} 2017 Wolters Kluwer Health, Inc. All rights reserved.",
year = "2018",
month = oct,
day = "1",
doi = "10.1097/MPH.0000000000000985",
language = "English (US)",
volume = "40",
pages = "e446--e449",
journal = "Journal of Pediatric Hematology/Oncology",
issn = "1077-4114",
publisher = "Lippincott Williams and Wilkins",
number = "7",
}