Successful use of anti-CD20 (rituximab) in severe, life-threatening childhood immune thrombocytopenic purpura

Kristi L. Bengtson; Michael A. Skinner; Russell E. Ware

doi:10.1067/S0022-3476(03)00446-3

Successful use of anti-CD20 (rituximab) in severe, life-threatening childhood immune thrombocytopenic purpura

Kristi L. Bengtson, Michael A. Skinner, Russell E. Ware

Surgery

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Thrombocytopenia with life-threatening hemorrhage in childhood immune thrombocytopenic purpura is rare, but effective therapeutic options are limited for the patient with bleeding. We report the efficacy of humanized anti-CD20 monoclonal antibody (rituximab, Rituxan) therapy for an infant with severe, refractory life-threatening immune thrombocytopenic purpura.

Original language	English (US)
Pages (from-to)	670-673
Number of pages	4
Journal	Journal of Pediatrics
Volume	143
Issue number	5
DOIs	https://doi.org/10.1067/S0022-3476(03)00446-3
State	Published - Nov 2003

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1067/S0022-3476(03)00446-3

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abstract = "Thrombocytopenia with life-threatening hemorrhage in childhood immune thrombocytopenic purpura is rare, but effective therapeutic options are limited for the patient with bleeding. We report the efficacy of humanized anti-CD20 monoclonal antibody (rituximab, Rituxan) therapy for an infant with severe, refractory life-threatening immune thrombocytopenic purpura.",

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AU - Skinner, Michael A.

AU - Ware, Russell E.

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N2 - Thrombocytopenia with life-threatening hemorrhage in childhood immune thrombocytopenic purpura is rare, but effective therapeutic options are limited for the patient with bleeding. We report the efficacy of humanized anti-CD20 monoclonal antibody (rituximab, Rituxan) therapy for an infant with severe, refractory life-threatening immune thrombocytopenic purpura.

AB - Thrombocytopenia with life-threatening hemorrhage in childhood immune thrombocytopenic purpura is rare, but effective therapeutic options are limited for the patient with bleeding. We report the efficacy of humanized anti-CD20 monoclonal antibody (rituximab, Rituxan) therapy for an infant with severe, refractory life-threatening immune thrombocytopenic purpura.

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Successful use of anti-CD20 (rituximab) in severe, life-threatening childhood immune thrombocytopenic purpura

Abstract

ASJC Scopus subject areas

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