TY - JOUR
T1 - Suction blister grafting for vitiligo
T2 - Efficacy and clinical predictive factors
AU - Gou, Darlene
AU - Currimbhoy, Sharif
AU - Pandya, Amit G.
N1 - Publisher Copyright:
© 2015 by the American Society for Dermatologic Surgery, Inc.
PY - 2015/5/8
Y1 - 2015/5/8
N2 - Background: Suction blister epidermal grafting (SBEG) is a well-established treatment modality for vitiligo, but predictive factors for outcomes are not well characterized. Objective: To determine the efficacy and predictive variables for response to SBEG in patients with vitiligo. Materials and methods: A retrospective single-center review of all cases treated with SBEG was performed. Repigmentation was assessed by 2 independent reviewers by assessing pigment spread of grafts during the postoperative period. Repigmentation rates were then compared with patient demographics and transplant location. Results: A total of 28 patients were enrolled in this study. The total number of grafts was 129, of which 86.8% (112/129) survived. Highest rate of graft survival was seen in patients younger than 20 years (100%) and the lowest in patients older than 40 years (75%-78%). Repigmentation was seen in 68% of patients. The highest degree of pigment spread was on the neck (283%) and face (231%), whereas the hands and feet had the least response (119%). Conclusion: Blister grafting is successful in most patients with vitiligo, with a high graft survival rate; however, the degree of pigment spread is variable and depends on clinical characteristics of the patient and graft site.
AB - Background: Suction blister epidermal grafting (SBEG) is a well-established treatment modality for vitiligo, but predictive factors for outcomes are not well characterized. Objective: To determine the efficacy and predictive variables for response to SBEG in patients with vitiligo. Materials and methods: A retrospective single-center review of all cases treated with SBEG was performed. Repigmentation was assessed by 2 independent reviewers by assessing pigment spread of grafts during the postoperative period. Repigmentation rates were then compared with patient demographics and transplant location. Results: A total of 28 patients were enrolled in this study. The total number of grafts was 129, of which 86.8% (112/129) survived. Highest rate of graft survival was seen in patients younger than 20 years (100%) and the lowest in patients older than 40 years (75%-78%). Repigmentation was seen in 68% of patients. The highest degree of pigment spread was on the neck (283%) and face (231%), whereas the hands and feet had the least response (119%). Conclusion: Blister grafting is successful in most patients with vitiligo, with a high graft survival rate; however, the degree of pigment spread is variable and depends on clinical characteristics of the patient and graft site.
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U2 - 10.1097/DSS.0000000000000341
DO - 10.1097/DSS.0000000000000341
M3 - Article
C2 - 25899886
AN - SCOPUS:84928950121
SN - 1076-0512
VL - 41
SP - 633
EP - 639
JO - Dermatologic Surgery
JF - Dermatologic Surgery
IS - 5
ER -