SU‐GG‐T‐439: Dosimetric Comparison of Compensator and Multi‐Leaf Collimator (MLC) Based Intensity Modulated Radiosurgery (IMRS)

X. Tang, N. Tyagi, J. Wang, R. Rice, G. White, K. Cashon, L. Vanderspek, T. Pawlicki, K. Murphy, S. Jiang

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: Multi‐leaf collimator (MLC) based intensity‐modulated radiosurgery (IMRS) often results in large number of monitor units (MU) for patients with multiple brain lesions. Compensator based IMRS, however, may dramatically reduce MU. The purpose of this study is to quantify the reduction of MU for IMRS of multiple brain lesions using solid tissue compensators. Method and Materials: Patients with multiple brain tumors were selected for our study. For each patient, Varian Eclipse TPS was used to generate an MLC based IMRS plan consisting of 10–11 coplanar beams. The prescription dose for a typical IMRS treatment is 1800–2000 cGy delivered in 1 fraction using a 6 MV photon beam. IMRS plans were generated on 2 patients. The optimal fluence maps from IMRS plan were exported to the compensator generating system to generate compensators for each field. The compensator files are imported back to Eclipse to calculate MUs for the compensator fields. Eclipse TPS was modified to allow compensator based planning and evaluation inside Eclipse. Finally, we compared MLC and compensator plans in terms of MUs and target and normal structure coverage. Results: Compensators offer superior resolution compared to MLCs and are easier and faster to plan. DVH analysis from both patients shows adequate target coverage for both IMRS and compensator plans. More sparing of normal tissues in compensator plan was observed sometimes. The MUs were reduced by factors of more than 3 compared to an MLC based IMRS plan. Conclusion: Compensator based IMRS can dramatically reduce the number of MU needed for multiple brain lesion radiosurgery as compared to an MLC based IMRS plan while preserve prescribed dose coverage. Conflict of Interest: This work is partially supported by.decimal Inc.

Original languageEnglish (US)
Number of pages1
JournalMedical Physics
Volume35
Issue number6
DOIs
StatePublished - 2008

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Radiosurgery
Brain
Conflict of Interest
Photons
Brain Neoplasms
Prescriptions

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

SU‐GG‐T‐439 : Dosimetric Comparison of Compensator and Multi‐Leaf Collimator (MLC) Based Intensity Modulated Radiosurgery (IMRS). / Tang, X.; Tyagi, N.; Wang, J.; Rice, R.; White, G.; Cashon, K.; Vanderspek, L.; Pawlicki, T.; Murphy, K.; Jiang, S.

In: Medical Physics, Vol. 35, No. 6, 2008.

Research output: Contribution to journalArticle

Tang, X. ; Tyagi, N. ; Wang, J. ; Rice, R. ; White, G. ; Cashon, K. ; Vanderspek, L. ; Pawlicki, T. ; Murphy, K. ; Jiang, S. / SU‐GG‐T‐439 : Dosimetric Comparison of Compensator and Multi‐Leaf Collimator (MLC) Based Intensity Modulated Radiosurgery (IMRS). In: Medical Physics. 2008 ; Vol. 35, No. 6.
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abstract = "Purpose: Multi‐leaf collimator (MLC) based intensity‐modulated radiosurgery (IMRS) often results in large number of monitor units (MU) for patients with multiple brain lesions. Compensator based IMRS, however, may dramatically reduce MU. The purpose of this study is to quantify the reduction of MU for IMRS of multiple brain lesions using solid tissue compensators. Method and Materials: Patients with multiple brain tumors were selected for our study. For each patient, Varian Eclipse TPS was used to generate an MLC based IMRS plan consisting of 10–11 coplanar beams. The prescription dose for a typical IMRS treatment is 1800–2000 cGy delivered in 1 fraction using a 6 MV photon beam. IMRS plans were generated on 2 patients. The optimal fluence maps from IMRS plan were exported to the compensator generating system to generate compensators for each field. The compensator files are imported back to Eclipse to calculate MUs for the compensator fields. Eclipse TPS was modified to allow compensator based planning and evaluation inside Eclipse. Finally, we compared MLC and compensator plans in terms of MUs and target and normal structure coverage. Results: Compensators offer superior resolution compared to MLCs and are easier and faster to plan. DVH analysis from both patients shows adequate target coverage for both IMRS and compensator plans. More sparing of normal tissues in compensator plan was observed sometimes. The MUs were reduced by factors of more than 3 compared to an MLC based IMRS plan. Conclusion: Compensator based IMRS can dramatically reduce the number of MU needed for multiple brain lesion radiosurgery as compared to an MLC based IMRS plan while preserve prescribed dose coverage. Conflict of Interest: This work is partially supported by.decimal Inc.",
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