Surface roughness & surface chemistry effects on protein adsorption

Brett Thomes, Richard Timmons, Robert Eberhart

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Protein adsorption studies on modified surfaces were carried out using human fibrinogen. The radiolabeled protein yield was typically greater than 95%. The extent of both initial protein adsorption and retention was remarkably independent of surface morphologies over the 5 to 100 nm mean roughness employed. However, protein adsorption was observed to be significantly affected by the nature of surface chemistry.

Original languageEnglish (US)
Title of host publicationSouthern Biomedical Engineering Conference - Proceedings
Place of PublicationPiscataway, NJ, United States
PublisherIEEE
Pages47
Number of pages1
StatePublished - 1998
EventProceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA
Duration: Feb 6 1998Feb 8 1998

Other

OtherProceedings of the 1998 17th Southern Biomedical Engineering Conference
CitySan Antonio, TX, USA
Period2/6/982/8/98

ASJC Scopus subject areas

  • Engineering(all)

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    Thomes, B., Timmons, R., & Eberhart, R. (1998). Surface roughness & surface chemistry effects on protein adsorption. In Southern Biomedical Engineering Conference - Proceedings (pp. 47). IEEE.