Surface treatments to improve the albumin affinity and blood compatibility of polymers

R. C. Eberhart

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The use of an albumin-gamma-globulin complex coating to solve the host-defense problems of foreign materials used in blood-contacting devices is under investigation. The approach that is described here is based on the discovery of a method to bind this serum protein to a number of polymer surfaces stably and conveniently. The method appears to have some practical advantages, and it utilizes a model that is useful for studying biological mechanisms for the organization of the blood-polymer interface. The development of this method and some biological results are described.

Original languageEnglish (US)
Pages (from-to)26-29
Number of pages4
JournalIEEE Engineering in Medicine and Biology Magazine
Volume8
Issue number2
StatePublished - Jun 1 1989

ASJC Scopus subject areas

  • Biomedical Engineering

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