Surface treatments to improve the albumin affinity and blood compatibility of polymers

R. C. Eberhart

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The use of an albumin-gamma-globulin complex coating to solve the host-defense problems of foreign materials used in blood-contacting devices is under investigation. The approach that is described here is based on the discovery of a method to bind this serum protein to a number of polymer surfaces stably and conveniently. The method appears to have some practical advantages, and it utilizes a model that is useful for studying biological mechanisms for the organization of the blood-polymer interface. The development of this method and some biological results are described.

Original languageEnglish (US)
Pages (from-to)26-29
Number of pages4
JournalIEEE Engineering in Medicine and Biology Magazine
Volume8
Issue number2
StatePublished - Jun 1989

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Surface treatment
Albumins
Polymers
Blood
gamma-Globulins
Proteins
Coatings
Blood Proteins
Equipment and Supplies
Globulins

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Cite this

Surface treatments to improve the albumin affinity and blood compatibility of polymers. / Eberhart, R. C.

In: IEEE Engineering in Medicine and Biology Magazine, Vol. 8, No. 2, 06.1989, p. 26-29.

Research output: Contribution to journalArticle

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