Surgical management of renal cell carcinoma

Laura Maria Krabbe, Aditya Bagrodia, Vitaly Margulis, Christopher G. Wood

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Surgical resection of renal cell carcinoma (RCC) is the benchmark for long-term cure of the disease. Although open or laparoscopic radical nephrectomy is considered the gold standard for stage T1b-T4 tumors, nephron-sparing surgery is the preferred operative modality for small renal masses demonstrating equivalent oncologic efficacy and improved renal function outcomes compared with complete nephrectomy. With the advance of minimally invasive surgery, nephron-sparing procedures can safely be conducted laparoscopically with or without robotic assistance. RCC with intravenous tumor thrombus presents a surgical challenge, but multidisciplinary surgical approaches can provide long-term benefit in these patients. The role of cytoreductive nephrectomy and metastasectomy in patients with metastatic RCC (mRCC) is controversial, but seems to be beneficial for patients in the era of targeted therapy.

Original languageEnglish (US)
Pages (from-to)27-32
Number of pages6
JournalSeminars in Interventional Radiology
Volume31
Issue number1
DOIs
StatePublished - 2014

Fingerprint

Nephrectomy
Renal Cell Carcinoma
Nephrons
Metastasectomy
Kidney
Benchmarking
Minimally Invasive Surgical Procedures
Robotics
Neoplasms
Thrombosis
Therapeutics

Keywords

  • nephron-sparing surgery
  • radical nephrectomy
  • renal cell carcinoma
  • surgical management

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Surgical management of renal cell carcinoma. / Krabbe, Laura Maria; Bagrodia, Aditya; Margulis, Vitaly; Wood, Christopher G.

In: Seminars in Interventional Radiology, Vol. 31, No. 1, 2014, p. 27-32.

Research output: Contribution to journalArticle

Krabbe, Laura Maria ; Bagrodia, Aditya ; Margulis, Vitaly ; Wood, Christopher G. / Surgical management of renal cell carcinoma. In: Seminars in Interventional Radiology. 2014 ; Vol. 31, No. 1. pp. 27-32.
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