Surveillance for Hepatocellular Carcinoma

Research output: Contribution to journalReview articlepeer-review

Abstract

Patients with cirrhosis of the liver have a very high risk for developing hepatocellular carcinoma (HCC). Therefore, this group of patients should undergo surveillance to improve mortality. Better tools for stratifying the risk of HCC among patients with cirrhosis are needed. The best strategy for surveillance is the combination of alpha-fetoprotein and ultrasound of the liver every 6 months. This strategy shows a sensitivity of approximately 65% and a specificity of 90%, and importantly, has been shown to improve mortality in these patients. Balancing benefits and harms should be performed when deciding to proceed with surveillance.

Original languageEnglish (US)
Pages (from-to)611-621
Number of pages11
JournalClinics in Liver Disease
Volume24
Issue number4
DOIs
StatePublished - Nov 2020

Keywords

  • Alpha-fetoprotein
  • Cirrhosis
  • Surveillance
  • Ultrasound

ASJC Scopus subject areas

  • Hepatology

Fingerprint Dive into the research topics of 'Surveillance for Hepatocellular Carcinoma'. Together they form a unique fingerprint.

Cite this