Susceptibility to lupus nephritis in the NZB/W model system

Laurence Morel, Edward K. Wakeland

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.

Original languageEnglish (US)
Pages (from-to)718-725
Number of pages8
JournalCurrent Opinion in Immunology
Volume10
Issue number6
DOIs
StatePublished - Dec 1998

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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