Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse

Medicine & Life Sciences

• Ro 48-8071 96%
• lanosterol synthase 77%
• Cholesterol 31%
• Sterols 10%
• Small Intestine 7%
• Lanosterol 6%
• Ezetimibe 5%
• Chylomicrons 5%
• Large Intestine 5%
• Messenger RNA 4%
• Liver 4%
• Lipoproteins 4%
• Genes 3%
• Histology 3%
• Stomach 3%
• Body Weight 3%
• Diet 2%
• Pharmacology 2%
• Staining and Labeling 2%
• Gene Expression 2%
• Therapeutics 0%

Chemical Compounds

• Ro 48-8071 100%
• Lanosterol 61%
• Cholesterol 38%
• Sterol 9%
• Ezetimibe 6%
• Lipoprotein 4%
• Plasma 2%
• Weight 2%
• Amount 1%