Sympathetic Neural and Hemodynamic Responses During Cold Pressor Test in Elderly Blacks and Whites

Yoshiyuki Okada, Sara S. Jarvis, Stuart A. Best, Jeffrey G. Edwards, Joseph M Hendrix, Beverley A Huet, Wanpen Vongpatanasin, Benjamin D Levine, Qi Fu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The sympathetic response during the cold pressor test (CPT) has been reported to be greater in young blacks than whites, especially in those with a family history of hypertension. Because blood pressure (BP) increases with age, we evaluated whether elderly blacks have greater sympathetic activation during CPT than age-matched whites. BP, heart rate, cardiac output, and muscle sympathetic nerve activity were measured during supine baseline, 2-minute CPT, and 3-minute recovery in 47 elderly (68±7 [SD] years) volunteers (12 blacks and 35 whites). Baseline BP, heart rate, cardiac output, or muscle sympathetic nerve activity did not differ between races. Systolic and diastolic BP and heart rate increased during CPT (all P0.05). Cardiac output increased during CPT and ≤30 s of recovery in both groups, but was lower in blacks than whites. Muscle sympathetic nerve activity increased during CPT in both groups (both P

Original languageEnglish (US)
JournalHypertension
DOIs
StateAccepted/In press - Mar 28 2016

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Hemodynamics
Blood Pressure
Cardiac Output
Heart Rate
Myocardium
hydroquinone
Volunteers
Hypertension
Muscles

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Sympathetic Neural and Hemodynamic Responses During Cold Pressor Test in Elderly Blacks and Whites. / Okada, Yoshiyuki; Jarvis, Sara S.; Best, Stuart A.; Edwards, Jeffrey G.; Hendrix, Joseph M; Huet, Beverley A; Vongpatanasin, Wanpen; Levine, Benjamin D; Fu, Qi.

In: Hypertension, 28.03.2016.

Research output: Contribution to journalArticle

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