Symptom improvement in women after fecal incontinence treatments

A multicenter cohort study of the pelvic floor disorders network

Alayne Markland, Lu Wang, J. Eric Jelovsek, Linda Brubaker, Ashook Tuteja, Alison C. Weidner, Andelka LoSavio, Marlene Corton, Susan Meikle, Holly E. Richter

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objectives: The study aims were to characterize women with fecal incontinence (FI) and measure changes in FI severity and quality of life 3 and 12 months after treatment. Methods: This study is a secondary analysis of a multicenter study measuring adaptive behaviors among women with FI. Women included had a primary complaint of at least monthly FI over 3 consecutive months and planned FI treatment. Demographic and medical history data were obtained at baseline. Data were collected at baseline, 3 months, and 12 months after clinically selected, nonstandardized treatment. Validated questionnaires were as follows: Fecal Incontinence Severity Index, Modified Manchester Health Questionnaire, Pelvic Floor Disorders Inventory's Colorectal and Anal Distress Inventory, Pelvic Floor Impact Questionnaire's Colorectal and Anal Impact Questionnaire, and Medical Outcomes Study Short Form. Questionnaire score changes from baseline were compared using paired t tests at 3 and 12 months after treatment. Results: Of the 133 women enrolled, 90 women had treatment data at 3 months and 77 at 12 months. Nonsurgical therapies were the most common (78%) with anal sphincter repair in 22%. Fecal Incontinence Severity Index scores and Modified Manchester Health Questionnaire scores significantly improved 3 months after nonsurgical and surgical treatments (-8.8 ± 12.0 and -12.6 ± 19.2, respectively, P < 0.001), as did Colorectal-Anal Distress Inventory and Colorectal-Anal Impact Questionnaire scores (-52.7 ± 70.0 and j60.6 ± 70.0, respectively, P < 0.001) and Medical Outcomes Study Short Form mental health scores (4.2 ± 9.4, P = 0.001). Improvement persisted 12 months posttreatment. Conclusions: In women seeking care for FI, symptom severity and condition-specific quality of life significantly improve within the first 3 months after FI treatment and are maintained up to 12 months.

Original languageEnglish (US)
Pages (from-to)46-52
Number of pages7
JournalFemale Pelvic Medicine and Reconstructive Surgery
Volume21
Issue number1
DOIs
StatePublished - 2015

Fingerprint

Pelvic Floor Disorders
Fecal Incontinence
Multicenter Studies
Cohort Studies
Therapeutics
Equipment and Supplies
Quality of Life
Outcome Assessment (Health Care)
Pelvic Floor
Psychological Adaptation
Health
Anal Canal
Surveys and Questionnaires
Mental Health
Demography

Keywords

  • Cohort study
  • Fecal incontinence
  • Nonsurgical treatment
  • Quality of life
  • Surgical treatment

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Surgery
  • Urology

Cite this

Symptom improvement in women after fecal incontinence treatments : A multicenter cohort study of the pelvic floor disorders network. / Markland, Alayne; Wang, Lu; Jelovsek, J. Eric; Brubaker, Linda; Tuteja, Ashook; Weidner, Alison C.; LoSavio, Andelka; Corton, Marlene; Meikle, Susan; Richter, Holly E.

In: Female Pelvic Medicine and Reconstructive Surgery, Vol. 21, No. 1, 2015, p. 46-52.

Research output: Contribution to journalArticle

Markland, Alayne ; Wang, Lu ; Jelovsek, J. Eric ; Brubaker, Linda ; Tuteja, Ashook ; Weidner, Alison C. ; LoSavio, Andelka ; Corton, Marlene ; Meikle, Susan ; Richter, Holly E. / Symptom improvement in women after fecal incontinence treatments : A multicenter cohort study of the pelvic floor disorders network. In: Female Pelvic Medicine and Reconstructive Surgery. 2015 ; Vol. 21, No. 1. pp. 46-52.
@article{e49488a9c72549e4866ad875de796739,
title = "Symptom improvement in women after fecal incontinence treatments: A multicenter cohort study of the pelvic floor disorders network",
abstract = "Objectives: The study aims were to characterize women with fecal incontinence (FI) and measure changes in FI severity and quality of life 3 and 12 months after treatment. Methods: This study is a secondary analysis of a multicenter study measuring adaptive behaviors among women with FI. Women included had a primary complaint of at least monthly FI over 3 consecutive months and planned FI treatment. Demographic and medical history data were obtained at baseline. Data were collected at baseline, 3 months, and 12 months after clinically selected, nonstandardized treatment. Validated questionnaires were as follows: Fecal Incontinence Severity Index, Modified Manchester Health Questionnaire, Pelvic Floor Disorders Inventory's Colorectal and Anal Distress Inventory, Pelvic Floor Impact Questionnaire's Colorectal and Anal Impact Questionnaire, and Medical Outcomes Study Short Form. Questionnaire score changes from baseline were compared using paired t tests at 3 and 12 months after treatment. Results: Of the 133 women enrolled, 90 women had treatment data at 3 months and 77 at 12 months. Nonsurgical therapies were the most common (78{\%}) with anal sphincter repair in 22{\%}. Fecal Incontinence Severity Index scores and Modified Manchester Health Questionnaire scores significantly improved 3 months after nonsurgical and surgical treatments (-8.8 ± 12.0 and -12.6 ± 19.2, respectively, P < 0.001), as did Colorectal-Anal Distress Inventory and Colorectal-Anal Impact Questionnaire scores (-52.7 ± 70.0 and j60.6 ± 70.0, respectively, P < 0.001) and Medical Outcomes Study Short Form mental health scores (4.2 ± 9.4, P = 0.001). Improvement persisted 12 months posttreatment. Conclusions: In women seeking care for FI, symptom severity and condition-specific quality of life significantly improve within the first 3 months after FI treatment and are maintained up to 12 months.",
keywords = "Cohort study, Fecal incontinence, Nonsurgical treatment, Quality of life, Surgical treatment",
author = "Alayne Markland and Lu Wang and Jelovsek, {J. Eric} and Linda Brubaker and Ashook Tuteja and Weidner, {Alison C.} and Andelka LoSavio and Marlene Corton and Susan Meikle and Richter, {Holly E.}",
year = "2015",
doi = "10.1097/SPV.0000000000000099",
language = "English (US)",
volume = "21",
pages = "46--52",
journal = "Female Pelvic Medicine and Reconstructive Surgery",
issn = "2151-8378",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Symptom improvement in women after fecal incontinence treatments

T2 - A multicenter cohort study of the pelvic floor disorders network

AU - Markland, Alayne

AU - Wang, Lu

AU - Jelovsek, J. Eric

AU - Brubaker, Linda

AU - Tuteja, Ashook

AU - Weidner, Alison C.

AU - LoSavio, Andelka

AU - Corton, Marlene

AU - Meikle, Susan

AU - Richter, Holly E.

PY - 2015

Y1 - 2015

N2 - Objectives: The study aims were to characterize women with fecal incontinence (FI) and measure changes in FI severity and quality of life 3 and 12 months after treatment. Methods: This study is a secondary analysis of a multicenter study measuring adaptive behaviors among women with FI. Women included had a primary complaint of at least monthly FI over 3 consecutive months and planned FI treatment. Demographic and medical history data were obtained at baseline. Data were collected at baseline, 3 months, and 12 months after clinically selected, nonstandardized treatment. Validated questionnaires were as follows: Fecal Incontinence Severity Index, Modified Manchester Health Questionnaire, Pelvic Floor Disorders Inventory's Colorectal and Anal Distress Inventory, Pelvic Floor Impact Questionnaire's Colorectal and Anal Impact Questionnaire, and Medical Outcomes Study Short Form. Questionnaire score changes from baseline were compared using paired t tests at 3 and 12 months after treatment. Results: Of the 133 women enrolled, 90 women had treatment data at 3 months and 77 at 12 months. Nonsurgical therapies were the most common (78%) with anal sphincter repair in 22%. Fecal Incontinence Severity Index scores and Modified Manchester Health Questionnaire scores significantly improved 3 months after nonsurgical and surgical treatments (-8.8 ± 12.0 and -12.6 ± 19.2, respectively, P < 0.001), as did Colorectal-Anal Distress Inventory and Colorectal-Anal Impact Questionnaire scores (-52.7 ± 70.0 and j60.6 ± 70.0, respectively, P < 0.001) and Medical Outcomes Study Short Form mental health scores (4.2 ± 9.4, P = 0.001). Improvement persisted 12 months posttreatment. Conclusions: In women seeking care for FI, symptom severity and condition-specific quality of life significantly improve within the first 3 months after FI treatment and are maintained up to 12 months.

AB - Objectives: The study aims were to characterize women with fecal incontinence (FI) and measure changes in FI severity and quality of life 3 and 12 months after treatment. Methods: This study is a secondary analysis of a multicenter study measuring adaptive behaviors among women with FI. Women included had a primary complaint of at least monthly FI over 3 consecutive months and planned FI treatment. Demographic and medical history data were obtained at baseline. Data were collected at baseline, 3 months, and 12 months after clinically selected, nonstandardized treatment. Validated questionnaires were as follows: Fecal Incontinence Severity Index, Modified Manchester Health Questionnaire, Pelvic Floor Disorders Inventory's Colorectal and Anal Distress Inventory, Pelvic Floor Impact Questionnaire's Colorectal and Anal Impact Questionnaire, and Medical Outcomes Study Short Form. Questionnaire score changes from baseline were compared using paired t tests at 3 and 12 months after treatment. Results: Of the 133 women enrolled, 90 women had treatment data at 3 months and 77 at 12 months. Nonsurgical therapies were the most common (78%) with anal sphincter repair in 22%. Fecal Incontinence Severity Index scores and Modified Manchester Health Questionnaire scores significantly improved 3 months after nonsurgical and surgical treatments (-8.8 ± 12.0 and -12.6 ± 19.2, respectively, P < 0.001), as did Colorectal-Anal Distress Inventory and Colorectal-Anal Impact Questionnaire scores (-52.7 ± 70.0 and j60.6 ± 70.0, respectively, P < 0.001) and Medical Outcomes Study Short Form mental health scores (4.2 ± 9.4, P = 0.001). Improvement persisted 12 months posttreatment. Conclusions: In women seeking care for FI, symptom severity and condition-specific quality of life significantly improve within the first 3 months after FI treatment and are maintained up to 12 months.

KW - Cohort study

KW - Fecal incontinence

KW - Nonsurgical treatment

KW - Quality of life

KW - Surgical treatment

UR - http://www.scopus.com/inward/record.url?scp=84927627145&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927627145&partnerID=8YFLogxK

U2 - 10.1097/SPV.0000000000000099

DO - 10.1097/SPV.0000000000000099

M3 - Article

VL - 21

SP - 46

EP - 52

JO - Female Pelvic Medicine and Reconstructive Surgery

JF - Female Pelvic Medicine and Reconstructive Surgery

SN - 2151-8378

IS - 1

ER -