Symptomatic Trichomonas vaginalis infection in the setting of severe nitroimidazole allergy

Successful treatment with boric acid

Christina Muzny, Arti Barnes, Leandro Mena

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

This report describes a patient with symptomatic Trichomonas vaginalis infection who was unable to tolerate nitroimidazole drugs because of severe hypersensitivity, for which desensitisation was not possible. Use of intravaginal clotrimazole, intravaginal paromomycin, intravaginal furazolidone, povidoneiodine douches, and oral nitazoxanide were unsuccessful in eradicating the patient's T. vaginalis infection. A 2-month course of intravaginal topical boric acid subsequently achieved a complete symptomatic cure and the patient remained T. vaginalis wet prep- and culture-negative 60 days after treatment.

Original languageEnglish (US)
Pages (from-to)389-391
Number of pages3
JournalSexual Health
Volume9
Issue number4
DOIs
StatePublished - 2012

Fingerprint

Trichomonas Infections
Nitroimidazoles
Trichomonas vaginalis
Hypersensitivity
nitazoxanide
Paromomycin
Furazolidone
Clotrimazole
Therapeutics
Pharmaceutical Preparations
boric acid

Keywords

  • clotrimazole
  • furazolidone
  • hypersensitivity
  • nitazoxanide
  • povidone-iodine

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

Cite this

Symptomatic Trichomonas vaginalis infection in the setting of severe nitroimidazole allergy : Successful treatment with boric acid. / Muzny, Christina; Barnes, Arti; Mena, Leandro.

In: Sexual Health, Vol. 9, No. 4, 2012, p. 389-391.

Research output: Contribution to journalArticle

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