Synaptic vesicle recycling as a substrate for neural plasticity

Tuhin Virmani, Ege T. Kavalali

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Chemical synapses are the principle nodes of communication between neurons and are critical for the processing and storage of information in the brain. They consist of two functionally and structurally distinct compartments: presynaptic terminals and postsynaptic specializations. Presynaptic terminals store and release neurotransmitter substances in membranous organelles named synaptic vesicles, whereas postsynaptic structures contain signaling molecules responsible for generation of neuronal responses to released neurotransmitters. This chapter is primarily devoted to discussion of the cellular mechanisms that can underlie forms of synaptic plasticity that arise from changes in the structure and function of presynaptic terminals. Here, we will discuss prevailing concepts regarding presynaptic forms of plasticity rather than providing an exhaustive review of existing literature. Several recent review papers give an excellent account of the topic and the literature, some of which will not be covered here in detail (Atwood and Karunanithi, 2002; Zucker and Regehr, 2002; Jahn et al., 2003; Murthy and De Camilli, 2003).

Original languageEnglish (US)
Title of host publicationSynaptic Plasticity and Transsynaptic Signaling
PublisherSpringer US
Pages255-272
Number of pages18
ISBN (Print)9780387254432, 038724008X, 9780387240084
DOIs
StatePublished - 2005

Fingerprint

Neuronal Plasticity
Synaptic Vesicles
Presynaptic Terminals
Neurotransmitter Agents
Information Storage and Retrieval
Automatic Data Processing
Organelles
Synapses
Neurons
Brain

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

Cite this

Virmani, T., & Kavalali, E. T. (2005). Synaptic vesicle recycling as a substrate for neural plasticity. In Synaptic Plasticity and Transsynaptic Signaling (pp. 255-272). Springer US. https://doi.org/10.1007/0-387-25443-9_16

Synaptic vesicle recycling as a substrate for neural plasticity. / Virmani, Tuhin; Kavalali, Ege T.

Synaptic Plasticity and Transsynaptic Signaling. Springer US, 2005. p. 255-272.

Research output: Chapter in Book/Report/Conference proceedingChapter

Virmani, T & Kavalali, ET 2005, Synaptic vesicle recycling as a substrate for neural plasticity. in Synaptic Plasticity and Transsynaptic Signaling. Springer US, pp. 255-272. https://doi.org/10.1007/0-387-25443-9_16
Virmani T, Kavalali ET. Synaptic vesicle recycling as a substrate for neural plasticity. In Synaptic Plasticity and Transsynaptic Signaling. Springer US. 2005. p. 255-272 https://doi.org/10.1007/0-387-25443-9_16
Virmani, Tuhin ; Kavalali, Ege T. / Synaptic vesicle recycling as a substrate for neural plasticity. Synaptic Plasticity and Transsynaptic Signaling. Springer US, 2005. pp. 255-272
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