Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

S. B. Rajur; A. Y. Merwade; L. D. Basanagoudar; P. V. Kulkarni

doi:10.1002/jps.2600780917

Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

S. B. Rajur, A. Y. Merwade, L. D. Basanagoudar, P. V. Kulkarni

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

Original language	English (US)
Pages (from-to)	780-782
Number of pages	3
Journal	Journal of Pharmaceutical Sciences
Volume	78
Issue number	9
DOIs	https://doi.org/10.1002/jps.2600780917
State	Published - Sep 1989

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Pharmaceutical Science

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title = "Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles",

abstract = "Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.",

author = "Rajur, {S. B.} and Merwade, {A. Y.} and Basanagoudar, {L. D.} and Kulkarni, {P. V.}",

year = "1989",

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AU - Merwade, A. Y.

AU - Basanagoudar, L. D.

AU - Kulkarni, P. V.

PY - 1989/9

Y1 - 1989/9

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AB - Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

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Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

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