Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

S. B. Rajur, A. Y. Merwade, L. D. Basanagoudar, P. V. Kulkarni

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

Original languageEnglish (US)
Pages (from-to)780-782
Number of pages3
JournalJournal of Pharmaceutical Sciences
Volume78
Issue number9
DOIs
StatePublished - Sep 1989

ASJC Scopus subject areas

  • Pharmaceutical Science

Fingerprint Dive into the research topics of 'Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles'. Together they form a unique fingerprint.

Cite this