Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

S. B. Rajur, A. Y. Merwade, L. D. Basanagoudar, P. V. Kulkarni

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

Original languageEnglish (US)
Pages (from-to)780-782
Number of pages3
JournalJournal of Pharmaceutical Sciences
Volume78
Issue number9
DOIs
StatePublished - 1989

Fingerprint

Indoles
Dimethylformamide

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmaceutical Science

Cite this

Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles. / Rajur, S. B.; Merwade, A. Y.; Basanagoudar, L. D.; Kulkarni, P. V.

In: Journal of Pharmaceutical Sciences, Vol. 78, No. 9, 1989, p. 780-782.

Research output: Contribution to journalArticle

Rajur, S. B. ; Merwade, A. Y. ; Basanagoudar, L. D. ; Kulkarni, P. V. / Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles. In: Journal of Pharmaceutical Sciences. 1989 ; Vol. 78, No. 9. pp. 780-782.
@article{078fd93076f5406980ab2502cb210203,
title = "Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles",
abstract = "Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.",
author = "Rajur, {S. B.} and Merwade, {A. Y.} and Basanagoudar, {L. D.} and Kulkarni, {P. V.}",
year = "1989",
doi = "10.1002/jps.2600780917",
language = "English (US)",
volume = "78",
pages = "780--782",
journal = "Journal of Pharmaceutical Sciences",
issn = "0022-3549",
publisher = "John Wiley and Sons Inc.",
number = "9",

}

TY - JOUR

T1 - Synthesis and antimicrobial activity of new substituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles

AU - Rajur, S. B.

AU - Merwade, A. Y.

AU - Basanagoudar, L. D.

AU - Kulkarni, P. V.

PY - 1989

Y1 - 1989

N2 - Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

AB - Ten new 4,8‐disubstituted 10‐methyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino(4,5‐a)indoles (5 and 6) were prepared by refluxing various 5‐substituted indole‐2‐carbohydrazides (4) with triethylorthoformate or triethylorthoacetate in dimethylformamide. These derivatives were evaluated for their antimicrobial activity. Some of the title compounds possess fairly potent antimicrobial activity.

UR - http://www.scopus.com/inward/record.url?scp=0024948938&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024948938&partnerID=8YFLogxK

U2 - 10.1002/jps.2600780917

DO - 10.1002/jps.2600780917

M3 - Article

C2 - 2585276

AN - SCOPUS:0024948938

VL - 78

SP - 780

EP - 782

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 9

ER -