Synthesis and utility of dihydropyridine boronic esters

Santanu Panda; Aaron Coffin; Q. Nhu Nguyen; Dean J. Tantillo; Joseph M. Ready

doi:10.1002/anie.201510027

Synthesis and utility of dihydropyridine boronic esters

Santanu Panda, Aaron Coffin, Q. Nhu Nguyen, Dean J. Tantillo, Joseph M. Ready

Research output: Contribution to journal › Article

20 Scopus citations

Abstract

When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.

Original language	English (US)
Pages (from-to)	2205-2209
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	55
Issue number	6
DOIs	https://doi.org/10.1002/anie.201510027
Publication status	Published - Feb 5 2016

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Keywords

allylic compounds
boron
heterocycles
samarium iodide
synthetic methods

ASJC Scopus subject areas

Chemistry(all)
Catalysis

Cite this

Panda, S., Coffin, A., Nguyen, Q. N., Tantillo, D. J., & Ready, J. M. (2016). Synthesis and utility of dihydropyridine boronic esters. Angewandte Chemie - International Edition, 55(6), 2205-2209. https://doi.org/10.1002/anie.201510027

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KW - heterocycles

KW - samarium iodide

KW - synthetic methods

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Access to Document

10.1002/anie.201510027