Synthesis and utility of dihydropyridine boronic esters

Santanu Panda, Aaron Coffin, Q. Nhu Nguyen, Dean J. Tantillo, Joseph M. Ready

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.

Original languageEnglish (US)
Pages (from-to)2205-2209
Number of pages5
JournalAngewandte Chemie - International Edition
Volume55
Issue number6
DOIs
StatePublished - Feb 5 2016

Fingerprint

Pyridine
Esters
Organometallics
1,4-dihydropyridine
pyridine
piperidine

Keywords

  • allylic compounds
  • boron
  • heterocycles
  • samarium iodide
  • synthetic methods

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Synthesis and utility of dihydropyridine boronic esters. / Panda, Santanu; Coffin, Aaron; Nguyen, Q. Nhu; Tantillo, Dean J.; Ready, Joseph M.

In: Angewandte Chemie - International Edition, Vol. 55, No. 6, 05.02.2016, p. 2205-2209.

Research output: Contribution to journalArticle

Panda, Santanu ; Coffin, Aaron ; Nguyen, Q. Nhu ; Tantillo, Dean J. ; Ready, Joseph M. / Synthesis and utility of dihydropyridine boronic esters. In: Angewandte Chemie - International Edition. 2016 ; Vol. 55, No. 6. pp. 2205-2209.
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