Synthesis of 12(S),20-, 12(S),19(R)-, and 12(S),19(S)-dihydroxyeicosa-cis-5,8,14-trans-10-tetraenoic acids, metabolites of 12(S)-hete

Sukumar Manna, Jacques Viala, Pendri Yadagiri, J R Falck

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Enantiospecific syntheses of the 20- and both 19-hydroxy metabolites of 12(S)-HETE were accomplished using readily available, chiral precursors.

Original languageEnglish (US)
Pages (from-to)2679-2682
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number24
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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