Synthesis of (±)-hepoxilin A3 utilizing arsonium ylides

P. Chabert, C. Mioskowski, J. R. Falck

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

(±)-Hepoxilin A3, a biologically active metabolite of arachidonic acid, was prepared from 1-heptyne and δ-valerolactone by a simple, convergent strategy that exploits arosnium ylides for homologation/functionalization.

Original languageEnglish (US)
Pages (from-to)2545-2548
Number of pages4
JournalTetrahedron Letters
Volume30
Issue number19
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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