Synthesis of oligopeptide and peptidomimetic libraries

Victor J. Hruby, Jung Mo Ahn, Subo Liao

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The elaboration of peptide libraries prepared by either chemical or biological methods in a format useful for discovery of peptides with specific biological activities was first introduced in the 1980s. A virtual explosion of activity in this area has occurred recently, and the basic approaches have been applied to a wide variety of chemistries and for all manner of biological, chemical and physical targets. Recent advances include new synthetic methodologies, new analytical methods, new design methods and new assay procedures.

Original languageEnglish (US)
Pages (from-to)114-119
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume1
Issue number1
StatePublished - Jun 1997

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Peptidomimetics
Peptide Library
Oligopeptides
Bioactivity
Explosions
Assays
Peptides

ASJC Scopus subject areas

  • Biochemistry

Cite this

Synthesis of oligopeptide and peptidomimetic libraries. / Hruby, Victor J.; Ahn, Jung Mo; Liao, Subo.

In: Current Opinion in Chemical Biology, Vol. 1, No. 1, 06.1997, p. 114-119.

Research output: Contribution to journalArticle

Hruby, Victor J. ; Ahn, Jung Mo ; Liao, Subo. / Synthesis of oligopeptide and peptidomimetic libraries. In: Current Opinion in Chemical Biology. 1997 ; Vol. 1, No. 1. pp. 114-119.
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