Synthesis of oligopeptide and peptidomimetic libraries

Victor J. Hruby, Jung Mo Ahn, Subo Liao

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The elaboration of peptide libraries prepared by either chemical or biological methods in a format useful for discovery of peptides with specific biological activities was first introduced in the 1980s. A virtual explosion of activity in this area has occurred recently, and the basic approaches have been applied to a wide variety of chemistries and for all manner of biological, chemical and physical targets. Recent advances include new synthetic methodologies, new analytical methods, new design methods and new assay procedures.

Original languageEnglish (US)
Pages (from-to)114-119
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume1
Issue number1
DOIs
StatePublished - Jun 1997

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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