Synthesis of side chain truncated apicularen A

A. Bhattacharjee, J. K. De Brabander

Research output: Contribution to journalArticlepeer-review

83 Scopus citations

Abstract

The potent cytostatic agent apicularen A belongs to a growing class of macrocyclic salicylates with unique biological properties. Herein, we present a short enantioselective synthesis of side chain truncated apicularen A.

Original languageEnglish (US)
Pages (from-to)8069-8073
Number of pages5
JournalTetrahedron Letters
Volume41
Issue number42
DOIs
StatePublished - Oct 14 2000

Keywords

  • Antitumor compounds
  • Hetero Diels-Alder
  • Natural products

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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