TY - JOUR
T1 - Systematic review of the incidence of sudden cardiac death in the United States
AU - Kong, Melissa H.
AU - Fonarow, Gregg C.
AU - Peterson, Eric D.
AU - Curtis, Anne B.
AU - Hernandez, Adrian F.
AU - Sanders, Gillian D.
AU - Thomas, Kevin L.
AU - Hayes, David L.
AU - Al-Khatib, Sana M.
N1 - Funding Information:
Dr. Kong serves on an advisory board to Medtronic, receives research funding from Biotronik , and was supported by a Ruth L. Kirschstein-National Research Service Award National Institutes of Health (NIH) grant ( 5-T32-DK-007731-15 ). The contents of this work are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. Dr. Fonarow receives research funding from the National Heart, Lung, and Blood Institute ; serves as a consultant for Novartis, Medtronic, and St. Jude Medical; and receives honoraria from GlaxoSmithKline, St. Jude Medical, and Medtronic. Dr. Peterson has received research support from Bristol-Myers Squibb/Sanofi , Merck/Schering-Plough , Lilly , and Johnson & Johnson . Dr. Curtis receives research funding from Medtronic and St. Jude Medical ; consulting, Speakers' Bureau, and/or fellowship support from Medtronic , St. Jude Medical , Biotronik , and Sanofi-Aventis ; and has served on the advisory board of Biosense Webster. Dr. Hernandez receives research funding from Johnson & Johnson and honorarium from Medtronic. Dr. Sanders is coinvestigator on a Medtronic Inc. research grant. Dr. Hayes serves on an advisory board for St. Jude Medical, Boston Scientific, and Pixel Velocity, and receives speaking honoraria from St. Jude Medical, Boston Scientific, Medtronic, Sorin Medical, Biotronik, and Blackwell-Futura. Dr. Al-Khatib has received research funding and speaking fees from Medtronic and Biotronik . All other authors have reported they have no relationships to disclose.
PY - 2011/2/15
Y1 - 2011/2/15
N2 - The need for consistent and current data describing the true incidence of sudden cardiac arrest (SCA) and/or sudden cardiac death (SCD) was highlighted during the most recent Sudden Cardiac Arrest Thought Leadership Alliance's (SCATLA) Think Tank meeting of national experts with broad representation of key stakeholders, including thought leaders and representatives from the American College of Cardiology, American Heart Association, and the Heart Rhythm Society. As such, to evaluate the true magnitude of this public health problem, we performed a systematic literature search in MEDLINE using the MeSH headings, "death, sudden" OR the terms "sudden cardiac death" OR "sudden cardiac arrest" OR "cardiac arrest" OR "cardiac death" OR "sudden death" OR "arrhythmic death." Study selection criteria included peer-reviewed publications of primary data used to estimate SCD incidence in the U.S. We used Web of Science's Cited Reference Search to evaluate the impact of each primary estimate on the medical literature by determining the number of times each "primary source" has been cited. The estimated U.S. annual incidence of SCD varied widely from 180,000 to >450,000 among 6 included studies. These different estimates were in part due to different data sources (with data age ranging from 1980 to 2007), definitions of SCD, case ascertainment criteria, methods of estimation/ extrapolation, and sources of case ascertainment. The true incidence of SCA and/or SCD in the U.S. remains unclear, with a wide range in the available estimates that are badly dated. As reliable estimates of SCD incidence are important for improving risk stratification and prevention, future efforts are clearly needed to establish uniform definitions of SCA and SCD and then to prospectively and precisely capture cases of SCA and SCD in the overall U.S. population.
AB - The need for consistent and current data describing the true incidence of sudden cardiac arrest (SCA) and/or sudden cardiac death (SCD) was highlighted during the most recent Sudden Cardiac Arrest Thought Leadership Alliance's (SCATLA) Think Tank meeting of national experts with broad representation of key stakeholders, including thought leaders and representatives from the American College of Cardiology, American Heart Association, and the Heart Rhythm Society. As such, to evaluate the true magnitude of this public health problem, we performed a systematic literature search in MEDLINE using the MeSH headings, "death, sudden" OR the terms "sudden cardiac death" OR "sudden cardiac arrest" OR "cardiac arrest" OR "cardiac death" OR "sudden death" OR "arrhythmic death." Study selection criteria included peer-reviewed publications of primary data used to estimate SCD incidence in the U.S. We used Web of Science's Cited Reference Search to evaluate the impact of each primary estimate on the medical literature by determining the number of times each "primary source" has been cited. The estimated U.S. annual incidence of SCD varied widely from 180,000 to >450,000 among 6 included studies. These different estimates were in part due to different data sources (with data age ranging from 1980 to 2007), definitions of SCD, case ascertainment criteria, methods of estimation/ extrapolation, and sources of case ascertainment. The true incidence of SCA and/or SCD in the U.S. remains unclear, with a wide range in the available estimates that are badly dated. As reliable estimates of SCD incidence are important for improving risk stratification and prevention, future efforts are clearly needed to establish uniform definitions of SCA and SCD and then to prospectively and precisely capture cases of SCA and SCD in the overall U.S. population.
KW - incidence
KW - sudden cardiac arrest
KW - sudden cardiac death
UR - http://www.scopus.com/inward/record.url?scp=79851476464&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79851476464&partnerID=8YFLogxK
U2 - 10.1016/j.jacc.2010.09.064
DO - 10.1016/j.jacc.2010.09.064
M3 - Review article
C2 - 21310315
AN - SCOPUS:79851476464
SN - 0735-1097
VL - 57
SP - 794
EP - 801
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 7
ER -