Systemic chemotherapy for psoriasis. A national survey

P. R. Bergstresser, S. H. Schreiber, G. D. Weinstein

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

A questionnaire that was mailed to 510 randomly selected dermatologists in the United States surveyed their use of three systemic chemotherapeutic agents for the treatment of psoriasis during the 2 yr period of 1973 to 1974. Methotrexate was used by 52% of the surveyed dermatologists, while hydroxyurea and azaribine were used by 10% and 2%, respectively. 75% of the dermatologists who used methotrexate treated 10 or fewer psoriatic patients with this drug. Multiple dose therapy with methotrexate divided over a period of 36 hr each wk was the preferred schedule of 66% of the dermatologists. Liver biopsy specimens and creatinine clearance tests were obtained for only 17% and 35% of patients, respectively, prior to initiating methotrexate therapy. The estimated number of dermatologist treated psoriatics nationwide receiving methotrexate is 25,000.

Original languageEnglish (US)
Pages (from-to)977-981
Number of pages5
JournalArchives of Dermatology
Volume112
Issue number7
DOIs
StatePublished - 1976

Fingerprint

Psoriasis
Methotrexate
Drug Therapy
Hydroxyurea
Creatinine
Appointments and Schedules
Therapeutics
Dermatologists
Surveys and Questionnaires
Biopsy
Liver
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Dermatology

Cite this

Bergstresser, P. R., Schreiber, S. H., & Weinstein, G. D. (1976). Systemic chemotherapy for psoriasis. A national survey. Archives of Dermatology, 112(7), 977-981. https://doi.org/10.1001/archderm.112.7.977

Systemic chemotherapy for psoriasis. A national survey. / Bergstresser, P. R.; Schreiber, S. H.; Weinstein, G. D.

In: Archives of Dermatology, Vol. 112, No. 7, 1976, p. 977-981.

Research output: Contribution to journalArticle

Bergstresser, PR, Schreiber, SH & Weinstein, GD 1976, 'Systemic chemotherapy for psoriasis. A national survey', Archives of Dermatology, vol. 112, no. 7, pp. 977-981. https://doi.org/10.1001/archderm.112.7.977
Bergstresser, P. R. ; Schreiber, S. H. ; Weinstein, G. D. / Systemic chemotherapy for psoriasis. A national survey. In: Archives of Dermatology. 1976 ; Vol. 112, No. 7. pp. 977-981.
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