Systems approaches for the study of metabolic cycles in yeast

Sunil Laxman, Benjamin P. Tu

Research output: Contribution to journalReview article

8 Scopus citations


Over four decades ago, the first oscillations in metabolism in yeast cells were reported. Since then, multiple forms of oscillatory behavior have been observed in yeast grown under a variety of continuous culturing environments. The remarkable synchrony of cells undergoing such oscillations has made them ideal subjects for investigation using systems-based approaches. Herein, we briefly summarize previous work on the characterization of such oscillations using systems approaches, and present the long-period, Yeast Metabolic Cycle as an excellent model system for deciphering the temporal organization of fundamental cellular and metabolic processes at unprecedented resolution.

Original languageEnglish (US)
Pages (from-to)599-604
Number of pages6
JournalCurrent Opinion in Genetics and Development
Issue number6
StatePublished - Dec 2010

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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