Abstract
We describe 2 patients with refractory inflammatory myositis who had an initial favorable response to intravenous immunoglobulin (IVIG) therapy. In contrast to all other reported cases, our patients reached a nadir in creatine phosphokinase (CPK) levels at 6 and 14 weeks after initiation of therapy, respectively, then experienced a relentless rise in CPK levels as well as a return of muscle weakness while still receiving IVIG. While IVIG may benefit some patients with refractory myositis, future studies must address the sustained efficacy of this agent.
Original language | English (US) |
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Pages (from-to) | 1144-1145 |
Number of pages | 2 |
Journal | Journal of Rheumatology |
Volume | 21 |
Issue number | 6 |
State | Published - Jan 1 1994 |
Keywords
- Dermatomyositis
- Intravenous immunoglobulin
- Myositis
- Polymyositis
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology