Targeted expression of teashirt induces ectopic eyes in Drosophila

Duojia Pan, Gerald M. Rubin

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

teashirt was initially identified as a gene required for the specification of the trunk segments in Drosophila embryogenesis and encodes a transcription factor with zinc finger motifs. We report here that targeted expression of teashirt in imaginal discs is sufficient to induce ectopic eye formation in non-eye tissues, a phenotype similar to that produced from targeted expression of eyeless, dachshund, and eyes absent. Furthermore, teashirt and eyeless induce the expression of each other, suggesting that teashirt is part of the gene network that functions to specify eye identity.

Original languageEnglish (US)
Pages (from-to)15508-15512
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume95
Issue number26
DOIs
StatePublished - Dec 22 1998

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Drosophila
Imaginal Discs
Gene Regulatory Networks
Zinc Fingers
Embryonic Development
Transcription Factors
Phenotype
Genes

ASJC Scopus subject areas

  • General

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Targeted expression of teashirt induces ectopic eyes in Drosophila. / Pan, Duojia; Rubin, Gerald M.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, No. 26, 22.12.1998, p. 15508-15512.

Research output: Contribution to journalArticle

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