Targeting breast cancer metastasis

Xin Jin, Ping Mu

Research output: Contribution to journalArticle

52 Scopus citations

Abstract

Metastasis is the leading cause of breast cancer-associated deaths. Despite the significant improvement in current therapies in extending patient life, 30-40% of patients may eventually suffer from distant relapse and succumb to the disease. Consequently, a deeper understanding of the metastasis biology is key to developing better treatment strategies and achieving long-lasting therapeutic efficacies against breast cancer. This review covers recent breakthroughs in the discovery of various metastatic traits that contribute to the metastasis cascade of breast cancer, which may provide novel avenues for therapeutic targeting.

Original languageEnglish (US)
Pages (from-to)23-34
Number of pages12
JournalBreast Cancer: Basic and Clinical Research
Volume9
DOIs
StatePublished - Sep 2 2015
Externally publishedYes

Keywords

  • Breast cancer
  • Metastasis
  • Metastatic traits
  • Precision medicine
  • Targeted therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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