TB or not TB: How Mycobacterium tuberculosis may evade drug treatment

Errol C. Friedberg, Paula L. Fischhaber

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In this issue of Cell, a study by Valerie Mizrahi and her colleagues (Boshoff et al., 2003) suggests that a putative error-prone DNA polymerase encoded by the dnaE2 gene of Mycobacterium tuberculosis may bypass certain types of DNA base damage, generating mutations. This may be an important mechanism for generating drug-resistant strains of M. tuberculosis.

Original languageEnglish (US)
Pages (from-to)139-140
Number of pages2
JournalCell
Volume113
Issue number2
DOIs
StatePublished - Apr 18 2003

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Drug therapy
DNA-Directed DNA Polymerase
Mycobacterium tuberculosis
Genes
DNA
Pharmaceutical Preparations
DNA Damage
Mutation

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

TB or not TB : How Mycobacterium tuberculosis may evade drug treatment. / Friedberg, Errol C.; Fischhaber, Paula L.

In: Cell, Vol. 113, No. 2, 18.04.2003, p. 139-140.

Research output: Contribution to journalArticle

Friedberg, Errol C. ; Fischhaber, Paula L. / TB or not TB : How Mycobacterium tuberculosis may evade drug treatment. In: Cell. 2003 ; Vol. 113, No. 2. pp. 139-140.
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