Tc-99m human serum albumin: A suitable agent for plasma volume measurements in man

S. S. Yang; E. L. Nickoloff; P. A. McIntyre; W. C. Maddrey; H. H. Mikesell; U. Scheffel; W. Kasecamp; N. P. MacAllister

Tc-99m human serum albumin: A suitable agent for plasma volume measurements in man

S. S. Yang, E. L. Nickoloff, P. A. McIntyre, W. C. Maddrey, H. H. Mikesell, U. Scheffel, W. Kasecamp, N. P. MacAllister

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Abstract

In 16 patients we have carried out simultaneous plasma-volume measurements with human serum albumins tagged with Tc-99m (Tc99m HSA) and I-131 (I-131 HSA). The correlation coefficient was 0.987. Tc-99m HSA, prepared from kits that predictably yield high labeling efficiency (and thereby negligible amounts of TcO₄-), is clearly a superior agent for repeat plasma volume determinations, because of its shorter half-life and the reduced radiation dose to the subject.

Original language	English (US)
Pages (from-to)	804-807
Number of pages	4
Journal	Journal of Nuclear Medicine
Volume	19
Issue number	7
State	Published - 1978

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Cite this

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title = "Tc-99m human serum albumin: A suitable agent for plasma volume measurements in man",

abstract = "In 16 patients we have carried out simultaneous plasma-volume measurements with human serum albumins tagged with Tc-99m (Tc99m HSA) and I-131 (I-131 HSA). The correlation coefficient was 0.987. Tc-99m HSA, prepared from kits that predictably yield high labeling efficiency (and thereby negligible amounts of TcO4-), is clearly a superior agent for repeat plasma volume determinations, because of its shorter half-life and the reduced radiation dose to the subject.",

author = "Yang, {S. S.} and Nickoloff, {E. L.} and McIntyre, {P. A.} and Maddrey, {W. C.} and Mikesell, {H. H.} and U. Scheffel and W. Kasecamp and MacAllister, {N. P.}",

year = "1978",

language = "English (US)",

volume = "19",

pages = "804--807",

journal = "Journal of Nuclear Medicine",

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TY - JOUR

T1 - Tc-99m human serum albumin

T2 - A suitable agent for plasma volume measurements in man

AU - Yang, S. S.

AU - Nickoloff, E. L.

AU - McIntyre, P. A.

AU - Maddrey, W. C.

AU - Mikesell, H. H.

AU - Scheffel, U.

AU - Kasecamp, W.

AU - MacAllister, N. P.

PY - 1978

Y1 - 1978

N2 - In 16 patients we have carried out simultaneous plasma-volume measurements with human serum albumins tagged with Tc-99m (Tc99m HSA) and I-131 (I-131 HSA). The correlation coefficient was 0.987. Tc-99m HSA, prepared from kits that predictably yield high labeling efficiency (and thereby negligible amounts of TcO4-), is clearly a superior agent for repeat plasma volume determinations, because of its shorter half-life and the reduced radiation dose to the subject.

AB - In 16 patients we have carried out simultaneous plasma-volume measurements with human serum albumins tagged with Tc-99m (Tc99m HSA) and I-131 (I-131 HSA). The correlation coefficient was 0.987. Tc-99m HSA, prepared from kits that predictably yield high labeling efficiency (and thereby negligible amounts of TcO4-), is clearly a superior agent for repeat plasma volume determinations, because of its shorter half-life and the reduced radiation dose to the subject.

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AN - SCOPUS:0018220310

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VL - 19

SP - 804

EP - 807

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

IS - 7

ER -

Tc-99m human serum albumin: A suitable agent for plasma volume measurements in man

Abstract

ASJC Scopus subject areas

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