In 16 patients we have carried out simultaneous plasma-volume measurements with human serum albumins tagged with Tc-99m (Tc99m HSA) and I-131 (I-131 HSA). The correlation coefficient was 0.987. Tc-99m HSA, prepared from kits that predictably yield high labeling efficiency (and thereby negligible amounts of TcO4-), is clearly a superior agent for repeat plasma volume determinations, because of its shorter half-life and the reduced radiation dose to the subject.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Nuclear Medicine|
|State||Published - Dec 1 1978|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging