Technetium-99m macroaggregated albumin: A new lung scanning agent

C. C. Peterson; F. J. Bonte

doi:10.1016/0020-708X(67)90101-9

Technetium-99m macroaggregated albumin: A new lung scanning agent

C. C. Peterson, F. J. Bonte

Radiology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc^99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc^99m may be the preferred agent for lung scanning.

Original language	English (US)
Pages (from-to)	201-202
Number of pages	2
Journal	The International Journal Of Applied Radiation And Isotopes
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/0020-708X(67)90101-9
State	Published - Mar 1967

ASJC Scopus subject areas

Radiation
Nuclear Energy and Engineering
Radiology Nuclear Medicine and imaging

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title = "Technetium-99m macroaggregated albumin: A new lung scanning agent",

abstract = "Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc99m may be the preferred agent for lung scanning.",

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AU - Peterson, C. C.

AU - Bonte, F. J.

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N2 - Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc99m may be the preferred agent for lung scanning.

AB - Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc99m may be the preferred agent for lung scanning.

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