Technetium-99m macroaggregated albumin

A new lung scanning agent

C. C. Peterson, F. J. Bonte

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc99m may be the preferred agent for lung scanning.

Original languageEnglish (US)
Pages (from-to)201-202
Number of pages2
JournalThe International Journal Of Applied Radiation And Isotopes
Volume18
Issue number3
StatePublished - Mar 1967

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Technetium
technetium
albumins
lungs
Albumins
Scanning
Lung
scanning
counting
rabbits
radiation dosage
Photons
Serum Albumin
Isotopes
half life
serums
Half-Life
Suspensions
isotopes
Rabbits

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Nuclear Energy and Engineering

Cite this

Technetium-99m macroaggregated albumin : A new lung scanning agent. / Peterson, C. C.; Bonte, F. J.

In: The International Journal Of Applied Radiation And Isotopes, Vol. 18, No. 3, 03.1967, p. 201-202.

Research output: Contribution to journalArticle

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AB - Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc99m may be the preferred agent for lung scanning.

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